Will it be "one of the most comprehensive screening programs ever to check whether chemicals can disrupt human hormones" or "a misleading $76 million waste"? The U.S. Environmental Protection Agency [3]'s (EPA's) Endocrine Disruptor Screening Program, which is slated to begin tests in 2008, is already controversial. Some scientists are warning that the program will: use "a breed of rat that is relatively insensitive to several known hormone-disrupting chemicals"; feed the rats a soy-based chow containing natural hormone disruptors that may complicate test results; pay little attention to prenatal chemical exposure; test a too-high dosage range; and possibly allow "chemical companies to tailor certain aspects of the tests." The EPA counters that the program was developed "in an open manner to protect it from special interests," and that "it is not worried" about chemical industry [4] involvement. Indeed, the EPA shaped the screening program with input "from people who may have financial interest in the outcome of the tests," using data from the American Chemistry Council [5] and a toxicologist who works as an industry consultant.